Gene
polrmt
- ID
- ZDB-GENE-030131-1528
- Name
- polymerase (RNA) mitochondrial (DNA directed)
- Symbol
- polrmt Nomenclature History
- Previous Names
-
- si:dkey-21e2.1
- si:dkeyp-74c5.5
- wu:fb73g10
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have DNA-directed 5'-3' RNA polymerase activity and mitochondrial promoter sequence-specific DNA binding activity. Predicted to be involved in mitochondrial transcription. Predicted to localize to mitochondrial DNA-directed RNA polymerase complex. Is expressed in brain; eye; and gut. Orthologous to human POLRMT (RNA polymerase mitochondrial).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1093 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| combined oxidative phosphorylation deficiency 55 | Alliance | Combined oxidative phosphorylation deficiency 55 | 619743 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR029262 | DNA-directed RNA polymerase, N-terminal |
| Domain | IPR046950 | DNA-directed RNA polymerase, C-terminal domain, phage-type |
| Family | IPR002092 | DNA-directed RNA polymerase, phage-type |
| Homologous_superfamily | IPR011990 | Tetratricopeptide-like helical domain superfamily |
| Homologous_superfamily | IPR037159 | DNA-directed RNA polymerase, N-terminal domain superfamily |
| Homologous_superfamily | IPR043502 | DNA/RNA polymerase superfamily |
| Repeat | IPR002885 | Pentatricopeptide repeat |
Domain Details Per Protein
| Protein | Length | DNA-directed RNA polymerase, C-terminal domain, phage-type | DNA-directed RNA polymerase, N-terminal | DNA-directed RNA polymerase, N-terminal domain superfamily | DNA-directed RNA polymerase, phage-type | DNA/RNA polymerase superfamily | Pentatricopeptide repeat | Tetratricopeptide-like helical domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4ILV6
|
1281 | |||||||
|
UniProtKB:A0A8M9PWF2
|
311 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
polrmt-201
(1)
|
Ensembl | 3,846 nt | ||
| mRNA |
polrmt-202
(1)
|
Ensembl | 777 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance