Gene

arg2

ID
ZDB-GENE-030131-1334
Name
arginase 2
Symbol
arg2 Nomenclature History
Previous Names
  • wu:fb67g02
  • zgc:85630
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to enable arginase activity and manganese ion binding activity. Predicted to be involved in urea cycle. Predicted to act upstream of or within arginine metabolic process. Predicted to be active in mitochondrion. Is expressed in axial mesoderm; central nervous system; forerunner cell group; and integument. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ARG2 (arginase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa6316Allele with one point mutationUnknownPremature StopENU
sa28149Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With arg2 Human Ortholog
No data available
Associated With arg2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR020855 Ureohydrolase, manganese-binding site
Family IPR006035 Ureohydrolase
Family IPR014033 Arginase
Homologous_superfamily IPR023696 Ureohydrolase domain superfamily
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Domain Details Per Protein
Protein Additional Resources Length Arginase Ureohydrolase Ureohydrolase domain superfamily Ureohydrolase, manganese-binding site
UniProtKB:Q6PH54 InterPro 347
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 13
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA arg2-201 (1) Ensembl 2,257 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Construct Regulatory Region Coding Sequence Species Tg Lines Citations
TgBAC(arg2:EGFP)
  • arg2
  • Danio rerio
2Hammond et al., 2023
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Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-12D10ZFIN Curated Data
EncodesESTfb67g02
EncodescDNAMGC:65793ZFIN Curated Data
EncodescDNAMGC:85630ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanARG214
Conserved genome location (synteny) (1)
Amino acid sequence comparison (3)
Citations
1 - 10 of 36
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