Gene
chpt1
- ID
- ZDB-GENE-030131-1325
- Name
- choline phosphotransferase 1
- Symbol
- chpt1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable diacylglycerol cholinephosphotransferase activity. Predicted to act upstream of or within phospholipid biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum membrane. Is expressed in several structures, including digestive system; notochord; polster; tegmentum; and yolk syncytial layer. Orthologous to human CHPT1 (choline phosphotransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55458 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa10461 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR048254 | CDP-alcohol phosphatidyltransferase, conserved site |
| Family | IPR000462 | CDP-alcohol phosphatidyltransferase |
| Family | IPR014472 | Choline/ethanolamine phosphotransferase |
| Homologous_superfamily | IPR043130 | CDP-alcohol phosphatidyltransferase, transmembrane domain |
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Domain Details Per Protein
| Protein | Length | CDP-alcohol phosphatidyltransferase | CDP-alcohol phosphatidyltransferase, conserved site | CDP-alcohol phosphatidyltransferase, transmembrane domain | Choline/ethanolamine phosphotransferase |
|---|---|---|---|---|---|
|
UniProtKB:Q7ZW02
|
382 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-234F20 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-11K24 | ZFIN Curated Data | |
| Encodes | EST | fb67a04 | ||
| Encodes | EST | fd50f07 | ||
| Encodes | cDNA | MGC:55458 | ZFIN Curated Data | |
| Has Artifact | EST | fb67a10 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_212624 (1) | 2578 nt | ||
| Genomic | GenBank:BX890572 (1) | 166208 nt | ||
| Polypeptide | UniProtKB:Q7ZW02 (1) | 382 aa |
- Uszczynska-Ratajczak, B., Sugunan, S., Kwiatkowska, M., Migdal, M., Carbonell-Sala, S., Sokol, A., Winata, C.L., Chacinska, A. (2022) Profiling subcellular localization of nuclear-encoded mitochondrial gene products in zebrafish. Life science alliance. 6(1):
- Zhang, J., Qian, L., Wang, C., Teng, M., Duan, M., Chen, X., Li, X., Wang, C. (2020) UPLC-TOF-MS/MS metabolomics analysis of zebrafish metabolism by spirotetramat. Environmental pollution (Barking, Essex : 1987). 266:115310
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Mariotti, M., Ridge, P.G., Zhang, Y., Lobanov, A.V., Pringle, T.H., Guigo, R., Hatfield, D.L., Gladyshev, V.N. (2012) Composition and Evolution of the Vertebrate and Mammalian Selenoproteomes. PLoS One. 7(3):e33066
- Hart, D.O., Raha, T., Lawson, N.D., and Green, M.R. (2007) Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3. Nature. 450(7172):1082-1085
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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