Gene
uqcrc2b
- ID
- ZDB-GENE-030131-1269
- Name
- ubiquinol-cytochrome c reductase core protein 2b
- Symbol
- uqcrc2b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to contribute to endopeptidase activity. Predicted to be involved in protein processing involved in protein targeting to mitochondrion. Predicted to localize to mitochondrial inner membrane and mitochondrial processing peptidase complex. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 5. Is expressed in gut and liver. Orthologous to human UQCRC2 (ubiquinol-cytochrome c reductase core protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7139233 (1 image)
- IMAGE:6905267 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex III deficiency nuclear type 5 | Alliance | Mitochondrial complex III deficiency, nuclear type 5 | 615160 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Metalloenzyme, LuxS/M16 peptidase-like | Peptidase M16, C-terminal | Peptidase M16, N-terminal | Peptidase M16, zinc-binding site |
|---|---|---|---|---|---|
|
UniProtKB:Q6IQ59
|
454 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
uqcrc2b-201
(1)
|
Havana | 1679 nt | |
| ncRNA |
uqcrc2b-002
(1)
|
Havana | 661 nt |
Interactions and Pathways
No data available
Plasmids
No data available