ZFIN ID: ZDB-GENE-030131-1259
Gene Name: haptoglobin
Gene Symbol: hp    Nomenclature History

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Previous Names: haptoglobin-like (1), HpL (1), hpl, wu:fb64e01

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Ambiguous Mapping Details/Browsers
Description: Predicted to have serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to extracellular space. Is expressed in intestine and liver. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; artery disease (multiple); gout; hyperglycemia; and obesity. Orthologous to several human genes including HP (haptoglobin).
Genome Resources: Alliance (1),  Gene:110437731 (1), 
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH hp HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
[Anhaptoglobinemia] 614081
[Hypohaptoglobinemia] 614081
DISEASE ASSOCIATED WITH hp VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Cellular Component extracellular space (more)
Molecular Function serine-type endopeptidase activity (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA hp-201 (1)    Ensembl 1495
hp-202 (1)    Ensembl 538
Browsers: NCBI
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM hp No data available
MARKER RELATIONSHIPS
hp Contained in: [BAC] DKEY-90B24 (order this)
hp Contains: [SNP] rs3728194 (1)
hp Has Artifact: [EST] fb64e01 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001366017 (1)
Genomic GenBank:CR382281 (1) 143523 nt
Select Tool
Polypeptide UniProtKB:F8W5P2 (1) 308 aa
Sequence Information (all 15)
ORTHOLOGY for hp ( Ambiguous )
CITATIONS (24)