Gene
nqo1
- ID
- ZDB-GENE-030131-1226
- Name
- NAD(P)H dehydrogenase, quinone 1
- Symbol
- nqo1 Nomenclature History
- Previous Names
-
- wu:fb63c10
- zgc:77191
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have NAD(P)H dehydrogenase (quinone) activity and electron transfer activity. Involved in cellular response to xenobiotic stimulus. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in several diseases, including asthma; hematologic cancer (multiple); lung disease (multiple); macular degeneration; and small cell carcinoma. Orthologous to human NQO1 (NAD(P)H quinone dehydrogenase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6901454 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Benzene toxicity, susceptibility to} | |||
| {Breast cancer, poor survival after chemotherapy for} | |||
| {Leukemia, post-chemotherapy, susceptibility to} |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Flavodoxin-like fold | Flavoprotein-like superfamily | NAD(P)H dehydrogenase (quinone) |
|---|---|---|---|---|
|
UniProtKB:A0A2R8PW65
|
289 | |||
|
UniProtKB:Q6P0H2
|
275 |
Interactions and Pathways
No data available
Plasmids
No data available