Gene
slc2a2
- ID
- ZDB-GENE-030131-1213
- Name
- solute carrier family 2 member 2
- Symbol
- slc2a2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Exhibits D-glucose transmembrane transporter activity. Involved in brain development; glucose import; and liver development. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in Fanconi syndrome; glycogen storage disease; and type 2 diabetes mellitus. Is expressed in several structures, including digestive system; muscle; nervous system; pleuroperitoneal region; and yolk syncytial layer. Orthologous to human SLC2A2 (solute carrier family 2 member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 29 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Marín-Juez et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Fanconi-Bickel syndrome | Alliance | Fanconi-Bickel syndrome | 227810 |
| type 2 diabetes mellitus | Alliance | {Diabetes mellitus, noninsulin-dependent} | 125853 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR005829 | Sugar transporter, conserved site |
| Domain | IPR020846 | Major facilitator superfamily domain |
| Family | IPR003663 | Sugar/inositol transporter |
| Family | IPR005828 | Major facilitator, sugar transporter-like |
| Family | IPR045263 | Glucose transporter GLUT |
| Homologous_superfamily | IPR036259 | MFS transporter superfamily |
Domain Details Per Protein
| Protein | Length | Glucose transporter GLUT | Major facilitator, sugar transporter-like | Major facilitator superfamily domain | MFS transporter superfamily | Sugar/inositol transporter | Sugar transporter, conserved site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q102R8
|
504 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc2a2-201
(1)
|
Ensembl | 2,792 nt | ||
| ncRNA |
slc2a2-002
(1)
|
Ensembl | 829 nt |
Interactions and Pathways
No data available
Plasmids