Gene

slc2a2

ID
ZDB-GENE-030131-1213
Name
solute carrier family 2 member 2
Symbol
slc2a2 Nomenclature History
Previous Names
  • glut2 (1)
  • wu:fb62h10
  • zglut2 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Exhibits D-glucose transmembrane transporter activity. Involved in brain development; glucose import; and liver development. Predicted to localize to integral component of membrane. Is expressed in several structures, including digestive system; muscle; nervous system; pleuroperitoneal region; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Fanconi syndrome; glycogen storage disease; and type 2 diabetes mellitus. Orthologous to human SLC2A2 (solute carrier family 2 member 2).
Genome Resources
Note
None
Expression
All Expression Data
18 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from MarĂ­n-Juez et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc2a2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
type 2 diabetes mellitus Alliance {Diabetes mellitus, noninsulin-dependent} 125853
Fanconi-Bickel syndrome 227810
Associated With slc2a2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR005829 Sugar transporter, conserved site
Domain IPR020846 Major facilitator superfamily domain
Family IPR003663 Sugar/inositol transporter
Family IPR005828 Major facilitator, sugar transporter-like
Homologous_superfamily IPR036259 MFS transporter superfamily
Domain Details Per Protein
Protein Length Major facilitator, sugar transporter-like Major facilitator superfamily domain MFS transporter superfamily Sugar/inositol transporter Sugar transporter, conserved site
UniProtKB:Q102R8 504
UniProtKB:B0UY92 504
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations