Gene
cs
- ID
- ZDB-GENE-030131-1058
- Name
- citrate synthase
- Symbol
- cs Nomenclature History
- Previous Names
-
- wu:fb58e04
- zgc:55507
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable citrate (Si)-synthase activity and identical protein binding activity. Acts upstream of or within response to activity. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix. Is expressed in brain; gill; heart; and muscle. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and hypertrophic cardiomyopathy. Orthologous to human CS (citrate synthase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55507 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR019810 | Citrate synthase active site |
| Family | IPR002020 | Citrate synthase |
| Family | IPR010109 | Citrate synthase, eukaryotic-type |
| Homologous_superfamily | IPR016142 | Citrate synthase-like, large alpha subdomain |
| Homologous_superfamily | IPR016143 | Citrate synthase-like, small alpha subdomain |
| Homologous_superfamily | IPR036969 | Citrate synthase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Citrate synthase | Citrate synthase active site | Citrate synthase, eukaryotic-type | Citrate synthase-like, large alpha subdomain | Citrate synthase-like, small alpha subdomain | Citrate synthase superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:B2GT34 | InterPro | 468 | ||||||
| UniProtKB:Q7ZVY5 | InterPro | 468 |
Interactions and Pathways
No data available
Plasmids
No data available