Gene

ephx5

ID
ZDB-GENE-030131-1050
Name
epoxide hydrolase 5
Symbol
ephx5 Nomenclature History
Previous Names
  • ephx1
  • ephx1l
  • wu:fb58c02
  • wu:fb62g01
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to enable epoxide hydrolase activity. Predicted to be involved in arachidonate metabolic process and epoxide metabolic process. Predicted to act upstream of or within lipid metabolic process and response to toxic substance. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in several diseases, including Leber hereditary optic neuropathy; anemia (multiple); hematologic cancer (multiple); respiratory system disease (multiple); and toxic encephalopathy. Orthologous to human EPHX1 (epoxide hydrolase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ephx5 Human Ortholog
No data available
Associated With ephx5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000073 Alpha/beta hydrolase fold-1
Domain IPR010497 Epoxide hydrolase, N-terminal
Family IPR000639 Epoxide hydrolase-like
Family IPR016292 Epoxide hydrolase
Homologous_superfamily IPR029058 Alpha/Beta hydrolase fold
Domain Details Per Protein
Protein Additional Resources Length Alpha/Beta hydrolase fold Alpha/beta hydrolase fold-1 Epoxide hydrolase Epoxide hydrolase-like Epoxide hydrolase, N-terminal
UniProtKB:A0A0R4IK35 InterPro 259
UniProtKB:A0A8M9QAE5 InterPro 480
UniProtKB:A0A8M2BK97 InterPro 478
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ephx5-201 (1) Ensembl 1,568 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations