Gene
mtx2
- ID
- ZDB-GENE-021210-2
- Name
- metaxin 2
- Symbol
- mtx2 Nomenclature History
- Previous Names
-
- fc02d09
- wu:fc02d09
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to be involved in mitochondrion organization. Predicted to act upstream of or within protein transport. Predicted to be located in membrane and mitochondrion. Predicted to be part of SAM complex. Predicted to be active in cytoplasm. Is expressed in blastoderm and female organism. Orthologous to human MTX2 (metaxin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:91837 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Mandibuloacral dysplasia progeroid syndrome | 619127 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR012336 | Thioredoxin-like fold |
| Domain | IPR033468 | Metaxin, glutathione S-transferase domain |
| Family | IPR040079 | Glutathione transferase family |
| Family | IPR050931 | Mitochondrial Protein Transport Metaxin |
| Homologous_superfamily | IPR036282 | Glutathione S-transferase, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Glutathione S-transferase, C-terminal domain superfamily | Glutathione transferase family | Metaxin, glutathione S-transferase domain | Mitochondrial Protein Transport Metaxin | Thioredoxin-like fold |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6WFZ4
|
274 |
Interactions and Pathways
No data available
Plasmids
No data available