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ZIRC
ZFIN ID: ZDB-GENE-021206-4
Gene Name: SEBOX homeobox
Gene Symbol: sebox    Nomenclature History

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Previous Names: mezzo (1), OG9 homeobox gene (1), og9x (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in endoderm development; heart morphogenesis; and regulation of transcription, DNA-templated. Predicted to localize to the nucleus. Is expressed in margin; marginal blastomere; presumptive endoderm; and shield. Orthologous to human SEBOX (SEBOX homeobox).
Genome Resources: Alliance (1),  Gene:282666 (1),  Ensembl(GRCz11):ENSDARG00000042526 (1)
GENE EXPRESSION
All Expression Data: 16 figures from 12 publications
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Gastrula:Shield (6.0h-8.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa33769 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-sebox N/A 3
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH sebox HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH sebox VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process endoderm development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA sebox-201 (1)    Ensembl 4528
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sebox
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(sebox:EGFP) sebox EGFP Danio rerio 1 5
    MARKER RELATIONSHIPS
    sebox Contained in: [BAC] CH211-110P13 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173227 (1) 4075 bp
    Genomic GenBank:BX957226 (1) 149414 bp
    Select Tool
    Polypeptide UniProtKB:Z4YID0 (1) 313 aa
    Sequence Clusters UniGene:86794 (1)
    Sequence Information (all 10)
    ORTHOLOGY for sebox ( Chr: 5 )
    CITATIONS (39)