ZFIN is now using GRCz12tu for Genomic Data
Gene
ets1
- ID
- ZDB-GENE-021115-5
- Name
- v-ets avian erythroblastosis virus E26 oncogene homolog 1
- Symbol
- ets1 Nomenclature History
- Previous Names
-
- ets1a
- cb516 (1)
- id:ibd1116
- zgc:110573
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables DNA binding activity and DNA-binding transcription factor activity. Acts upstream of or within blood vessel endothelial cell differentiation; blood vessel morphogenesis; and regulation of endothelial cell apoptotic process. Is expressed in several structures, including cardiovascular system; germ ring; mesoderm; nervous system; and neural crest. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ETS1 (ETS proto-oncogene 1, transcription factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 42 figures from 16 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb516 (29 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chetty et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Ets1, N-terminal flanking region of Ets domain | Pointed domain | Protein C-ets-1, pointed domain | Sterile alpha motif/pointed domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q568B4 | InterPro | 334 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
- Genome Browsers