Gene

ets1

ID
ZDB-GENE-021115-5
Name
v-ets avian erythroblastosis virus E26 oncogene homolog 1
Symbol
ets1 Nomenclature History
Previous Names
  • ets1a
  • cb516 (1)
  • id:ibd1116
  • zgc:110573
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Exhibits DNA binding activity and DNA-binding transcription factor activity. Involved in blood vessel morphogenesis. Predicted to localize to nucleus. Is expressed in several structures, including cardiovascular system; germ ring; hematopoietic system; mesoderm; and nervous system. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ETS1 (ETS proto-oncogene 1, transcription factor).
Genome Resources
Note
None
Expression
All Expression Data
38 figures from 14 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ets1 Human Ortholog
No data available
Associated With ets1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000418 Ets domain
Domain IPR003118 Pointed domain
Domain IPR041886 Protein C-ets-1, pointed domain
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Ets domain Pointed domain Protein C-ets-1, pointed domain Sterile alpha motif/pointed domain superfamily Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:A0A076VF89 432
UniProtKB:A0A2R8QBT1 265
UniProtKB:F1Q9C1 266
UniProtKB:Q568B4 334
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations