Gene

smoc2

ID
ZDB-GENE-021031-5
Name
SPARC related modular calcium binding 2
Symbol
smoc2 Nomenclature History
Previous Names
  • cb488 (1)
  • wu:fb75d10
  • zgc:112171
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to enable calcium ion binding activity. Acts upstream of or within several processes, including embryonic viscerocranium morphogenesis; myeloid cell development; and regulation of BMP signaling pathway. Predicted to be located in collagen-containing extracellular matrix. Is expressed in several structures, including digestive system; ectoderm; nervous system; notochord; and optic vesicle. Orthologous to human SMOC2 (SPARC related modular calcium binding 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa24829Allele with one point mutationUnknownSplice SiteENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
1 - 1 of 1
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-smoc2N/ABloch-Zupan et al., 2011
MO2-smoc2N/ABloch-Zupan et al., 2011
MO3-smoc2N/AMelvin et al., 2013
MO4-smoc2N/AMelvin et al., 2013
MO5-smoc2N/AMommaerts et al., 2014
MO6-smoc2N/AMommaerts et al., 2014
1 - 6 of 6
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Human Disease
Associated With smoc2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
dentin dysplasia Alliance Dentin dysplasia, type I, with microdontia and misshapen teeth 125400
1 - 1 of 1
Associated With smoc2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein Additional Resources Length
UniProtKB:A0AB32T1Q2 InterPro 463
1 - 1 of 1
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA smoc2-201 (1)
Ensembl
Ensembl 507 nt
ZFIN BLAST
mRNA smoc2-202 (1)
Ensembl
Ensembl 1,314 nt
ZFIN BLAST
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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