Gene
plod3
- ID
- ZDB-GENE-021031-4
- Name
- procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
- Symbol
- plod3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have procollagen glucosyltransferase activity and procollagen-lysine 5-dioxygenase activity. Involved in motor neuron axon guidance and neural crest cell migration. Predicted to localize to endoplasmic reticulum. Is expressed in several structures, including axis; chordo neural hinge; mesoderm; pectoral fin; and splanchnocranium. Orthologous to human PLOD3 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb479 (16 images)
- cb816 (11 images)
- IMAGE:6912725 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- 22 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| BCARD syndrome (lysyl hydroxylase 3 deficiency) | 612394 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR001006 | Procollagen-lysine 5-dioxygenase, conserved site |
| Domain | IPR005123 | Oxoglutarate/iron-dependent dioxygenase domain |
| Domain | IPR006620 | Prolyl 4-hydroxylase, alpha subunit |
| Domain | IPR044861 | Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain |
| Family | IPR050757 | Collagen-modifying Glycosyltransferase 25 |
| Homologous_superfamily | IPR029044 | Nucleotide-diphospho-sugar transferases |
Domain Details Per Protein
| Protein | Length | Collagen-modifying Glycosyltransferase 25 | Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain | Nucleotide-diphospho-sugar transferases | Oxoglutarate/iron-dependent dioxygenase domain | Procollagen-lysine 5-dioxygenase, conserved site | Prolyl 4-hydroxylase, alpha subunit |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A3KNH4
|
730 | ||||||
|
UniProtKB:A0A8M2B9A3
|
686 |
Interactions and Pathways
No data available
Plasmids
No data available