pwp2h

ID

ZDB-GENE-021031-3

Name

PWP2 small subunit processome component

Symbol

pwp2h Nomenclature History

Previous Names

cb471 (1)
titania (1)
tti
zgc:56063

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Acts upstream of or within digestive system development and ribosomal small subunit assembly. Predicted to be located in nucleus. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Is expressed in several structures, including brain; digestive system; head; immature eye; and mesoderm. Orthologous to human PWP2 (PWP2 small subunit processome component).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb471 (20 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from Boglev et al., 2013
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pwp2h Human Ortholog

No data available

Associated With pwp2h Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019775	WD40 repeat, conserved site
Domain	IPR007148	Small-subunit processome, Utp12
Family	IPR027145	Periodic tryptophan protein 2
Homologous_superfamily	IPR011047	Quinoprotein alcohol dehydrogenase-like superfamily
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Repeat	IPR001680	WD40 repeat
Repeat	IPR020472	G-protein beta WD-40 repeat