Gene

ccnf

ID
ZDB-GENE-021030-2
Name
cyclin F
Symbol
ccnf Nomenclature History
Previous Names
  • cb443 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in several processes, including cellular protein metabolic process; negative regulation of centrosome duplication; and regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to localize to several cellular components, including SCF ubiquitin ligase complex; cyclin-dependent protein kinase holoenzyme complex; and microtubule organizing center. Is expressed in several structures, including margin; nervous system; optic vesicle; tail bud; and ventral mesoderm. Orthologous to human CCNF (cyclin F).
Genome Resources
Note
None
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ccnf Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Frontotemporal dementia and/or amyotrophic lateral sclerosis 5 619141
Associated With ccnf Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001810 F-box domain
Domain IPR004367 Cyclin, C-terminal domain
Domain IPR006671 Cyclin, N-terminal
Domain IPR013763 Cyclin-like
Family IPR028857 Cyclin-F, metazoan
Family IPR039361 Cyclin
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Homologous_superfamily IPR036047 F-box-like domain superfamily
Homologous_superfamily IPR036915 Cyclin-like superfamily
Domain Details Per Protein
Protein Length Cyclin Cyclin, C-terminal domain Cyclin-F, metazoan Cyclin-like Cyclin-like superfamily Cyclin, N-terminal F-box domain F-box-like domain superfamily Leucine-rich repeat domain superfamily
UniProtKB:Q6NYX6 764
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations