Gene

lgmn

ID
ZDB-GENE-021030-1
Name
legumain
Symbol
lgmn Nomenclature History
Previous Names
  • AEP (1)
  • cb173 (1)
  • cb460 (1)
  • sb:cb173
  • wu:fa98g05
  • wu:fj92g08
  • zgc:76953
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have cysteine-type endopeptidase activity. Involved in axon regeneration; negative regulation of ossification; and tissue regeneration. Is expressed in several structures, including cardiovascular system; immature eye; mesoderm; nervous system; and pleuroperitoneal region. Orthologous to human LGMN (legumain).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
17 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Jafari et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lgmn Human Ortholog
No data available
Associated With lgmn Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR048501 Legumain, prodomain
Family IPR001096 Peptidase C13, legumain
Family IPR043577 Asparaginyl endopeptidase
Homologous_superfamily IPR046427 Legumain prodomain superfamily
Domain Details Per Protein
Protein Length Asparaginyl endopeptidase Legumain, prodomain Legumain prodomain superfamily Peptidase C13, legumain
UniProtKB:Q6NYJ7 438
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA lgmn-201 (1) Ensembl 822 nt
mRNA lgmn-202 (1) Ensembl 2,358 nt
mRNA lgmn-203 (1) Ensembl 3,991 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations