Gene
stt3a
- ID
- ZDB-GENE-021015-3
- Name
- STT3 oligosaccharyltransferase complex catalytic subunit A
- Symbol
- stt3a Nomenclature History
- Previous Names
-
- cb437 (1)
- itm1
- wu:fb38c11
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have dolichyl-diphosphooligosaccharide-protein glycotransferase activity. Predicted to be involved in post-translational protein modification and protein N-linked glycosylation via asparagine. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Iw. Is expressed in axial mesoderm; hatching gland; musculature system; notochord; and otic placode. Orthologous to human STT3A (STT3 oligosaccharyltransferase complex catalytic subunit A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb437 (12 images)
- IMAGE:7143563 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital disorder of glycosylation Iw | Alliance | Congenital disorder of glycosylation, type Iw, autosomal recessive | 615596 |
| Congenital disorder of glycosylation, type Iw, autosomal dominant | 619714 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Oligosaccharyl transferase STT3, N-terminal domain | Oligosaccharyl transferase, STT3 subunit |
|---|---|---|---|
|
UniProtKB:Q7ZUY9
|
705 |
Interactions and Pathways
No data available
Plasmids
No data available