ZFIN is now using GRCz12tu for Genomic Data
Gene
mapk14b
- ID
- ZDB-GENE-021007-1
- Name
- mitogen-activated protein kinase 14b
- Symbol
- mapk14b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable MAP kinase activity. Predicted to be involved in several processes, including p38MAPK cascade; positive regulation of cell differentiation; and positive regulation of myoblast fusion. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in colon cancer; colorectal carcinoma; nasopharynx carcinoma; and rectum cancer. Orthologous to human MAPK14 (mitogen-activated protein kinase 14).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Krens et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Conserved_site | IPR003527 | Mitogen-activated protein (MAP) kinase, conserved site |
| Domain | IPR000719 | Protein kinase domain |
| Family | IPR008352 | Mitogen-activated protein (MAP) kinase p38-like |
| Family | IPR050117 | Mitogen-activated protein kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Mitogen-activated protein kinase | Mitogen-activated protein (MAP) kinase, conserved site | Mitogen-activated protein (MAP) kinase p38-like | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1RAA2 | InterPro | 361 | ||||||
| UniProtKB:Q9DGE1 | InterPro | 348 | ||||||
| UniProtKB:F1QQ40 | InterPro | 361 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mapk14b-201
(1)
|
Ensembl | 4,174 nt | ||
| mRNA |
mapk14b-202
(1)
|
Ensembl | 1,838 nt | ||
| mRNA |
mapk14b-203
(1)
|
Ensembl | 1,531 nt | ||
| ncRNA |
mapk14b-004
(1)
|
Ensembl | 773 nt | ||
| ncRNA |
mapk14b-005
(1)
|
Ensembl | 806 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers