header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-020419-2
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.
Gene Name: ribosomal protein L35
Gene Symbol: rpl35    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: CHUNP6863

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have mRNA binding activity. Involved in chordate embryonic development; erythrocyte differentiation; and regulation of cell cycle. Predicted to localize to the cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia. Orthologous to human RPL35 (ribosomal protein L35).
Genome Resources: Alliance (1),  Gene:192299 (1),  Ensembl(GRCz11):ENSDARG00000018334 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66402]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi258Tg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-rpl35 N/A 3
    PHENOTYPE
    Data: 11 figures from 8 publications
    Observed in:
    DISEASE ASSOCIATED WITH rpl35 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    ?Diamond-Blackfan anemia 19 618312
    DISEASE ASSOCIATED WITH rpl35 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chordate embryonic development (more)
    Cellular Component ribosome (more)
    Molecular Function structural constituent of ribosome (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001854 (1)
  • InterPro:IPR018254 (1)
  • InterPro:IPR036049 (1)
  • PROSITE:PS00579 (1)
  • Pfam:PF00831 (1)
    • TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rpl35 No data available
    MARKER RELATIONSHIPS
    rpl35 Encodes: [BAC END] zk4c2.t7
    [cDNA] MGC:66402 (1) (order this)
    rpl35 Has Artifact: [cDNA] MGC:158620 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173233 (1)
    Select Tool
    Genomic GenBank:CABZ01071016 (1)
    Select Tool
    Polypeptide UniProtKB:Q8JHJ1 (1) 123 aa
    Select Tool
    Sequence Clusters UniGene:119727 (1)
    Sequence Information (all 15)
    ORTHOLOGY for rpl35 ( Chr: 21 )
    CITATIONS (39)