Gene

tpi1b

ID
ZDB-GENE-020416-4
Name
triosephosphate isomerase 1b
Symbol
tpi1b Nomenclature History
Previous Names
  • cb179 (1)
  • DrTPI-B (1)
  • wu:fb51c02
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have methylglyoxal synthase activity; protein homodimerization activity; and triose-phosphate isomerase activity. Predicted to be involved in several processes, including gluconeogenesis; glyceraldehyde-3-phosphate biosynthetic process; and methylglyoxal biosynthetic process. Predicted to localize to cytosol. Is expressed in several structures, including brain; cardiovascular system; mesoderm; musculature system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in carbohydrate metabolic disorder and triosephosphate isomerase deficiency. Orthologous to human TPI1 (triosephosphate isomerase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tpi1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
triosephosphate isomerase deficiency Alliance Hemolytic anemia due to triosephosphate isomerase deficiency 615512
Associated With tpi1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR020861 Triosephosphate isomerase, active site
Family IPR000652 Triosephosphate isomerase
Family IPR022896 Triosephosphate isomerase, bacterial/eukaryotic
Homologous_superfamily IPR013785 Aldolase-type TIM barrel
Homologous_superfamily IPR035990 Triosephosphate isomerase superfamily
Domain Details Per Protein
Protein Length Aldolase-type TIM barrel Triosephosphate isomerase Triosephosphate isomerase, active site Triosephosphate isomerase, bacterial/eukaryotic Triosephosphate isomerase superfamily
UniProtKB:A0A0R4IGG3 248
UniProtKB:Q90XG0 248
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations