Gene
glra4b
- ID
- ZDB-GENE-020402-2
- Name
- glycine receptor, alpha 4b
- Symbol
- glra4b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Exhibits extracellularly glycine-gated ion channel activity. Predicted to contribute to extracellularly glycine-gated chloride channel activity and glycine binding activity. Predicted to be involved in several processes, including chloride transmembrane transport; glycinergic synaptic transmission; and neuropeptide signaling pathway. Predicted to localize to integral component of plasma membrane; neuron projection; and synapse. Is expressed in brain; hindbrain; retinal ganglion cell layer; retinal inner nuclear layer; and spinal cord. Orthologous to human GLRA4 (glycine receptor alpha 4 (pseudogene)).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018000 | Neurotransmitter-gated ion-channel, conserved site |
| Domain | IPR006029 | Neurotransmitter-gated ion-channel transmembrane domain |
| Domain | IPR006202 | Neurotransmitter-gated ion-channel ligand-binding domain |
| Family | IPR006028 | Gamma-aminobutyric acid A receptor/Glycine receptor alpha |
| Family | IPR006201 | Neurotransmitter-gated ion-channel |
| Family | IPR008127 | Glycine receptor alpha |
| Homologous_superfamily | IPR036719 | Neurotransmitter-gated ion-channel transmembrane domain superfamily |
| Homologous_superfamily | IPR036734 | Neurotransmitter-gated ion-channel ligand-binding domain superfamily |
| Homologous_superfamily | IPR038050 | Neuronal acetylcholine receptor |
Domain Details Per Protein
| Protein | Length | Gamma-aminobutyric acid A receptor/Glycine receptor alpha | Glycine receptor alpha | Neuronal acetylcholine receptor | Neurotransmitter-gated ion-channel | Neurotransmitter-gated ion-channel, conserved site | Neurotransmitter-gated ion-channel ligand-binding domain | Neurotransmitter-gated ion-channel ligand-binding domain superfamily | Neurotransmitter-gated ion-channel transmembrane domain | Neurotransmitter-gated ion-channel transmembrane domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5U3C8
|
532 | |||||||||
|
UniProtKB:A0A8M1P2L1
|
492 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
glra4b-201
(1)
|
Ensembl | 1,926 nt |
Interactions and Pathways
No data available
Plasmids
No data available