ZFIN ID: ZDB-GENE-020228-2
Gene Name: spalt-like transcription factor 1a
Gene Symbol: sall1a    Nomenclature History

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Previous Names: sall1 (1), spa1a (1), spalt1a (1), cb896 (1), id:ibd5077, sb:eu809

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity. Involved in embryonic pectoral fin morphogenesis and positive regulation of fibroblast growth factor receptor signaling pathway. Predicted to localize to nucleus. Is expressed in several structures, including fin; nervous system; neural keel; neural tube; and tail bud. Human ortholog(s) of this gene implicated in Townes-Brocks syndrome and middle lobe syndrome. Orthologous to human SALL1 (spalt like transcription factor 1).
Genome Resources: Alliance (1),  Gene:555721 (1),  Ensembl(GRCz11):ENSDARG00000074319 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa11237 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38627 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40952 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-sall1a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH sall1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Townes-Brocks syndrome Alliance Townes-Brocks branchiootorenal-like syndrome 107480
    Townes-Brocks syndrome 1 107480
    DISEASE ASSOCIATED WITH sall1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of fibroblast growth factor receptor signaling pathway (more)
    Cellular Component nucleus (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA sall1a-201 (1)    Ensembl 6552
    sall1a-202 (1)    Ensembl 6651
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sall1a No data available
    MARKER RELATIONSHIPS
    sall1a Contained in: [BAC] DKEY-245J10 (1) (order this)
    sall1a Contains: [SSLP] z26643 (1)
    sall1a Encodes: [EST] cb896 (1) (order this), eu809 (1), ibd5077
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001146014 (1) 5158 nt
    Genomic RefSeq:NW_018394702 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:F1QI36 (1) 1313 aa
    Sequence Information (all 22)
    ORTHOLOGY for sall1a ( Chr: 7 )
    CITATIONS (29)