Gene
mt-nd5
- ID
- ZDB-GENE-011205-12
- Name
- NADH dehydrogenase 5, mitochondrial
- Symbol
- mt-nd5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: MT Mapping Details/Browsers
- Description
- Predicted to have NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in ATP synthesis coupled electron transport. Predicted to localize to integral component of membrane; mitochondrial inner membrane; and respirasome. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and MELAS syndrome. Orthologous to human MT-ND5 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001516 | NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal |
| Domain | IPR001750 | NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit |
| Domain | IPR010934 | NADH dehydrogenase subunit 5, C-terminal |
| Family | IPR003945 | NADH-quinone oxidoreductase, chain 5-like |
| Family | IPR018393 | NADH-plastoquinone oxidoreductase, chain 5 subgroup |
Domain Details Per Protein
| Protein | Length | NADH dehydrogenase subunit 5, C-terminal | NADH-plastoquinone oxidoreductase, chain 5 subgroup | NADH-quinone oxidoreductase, chain 5-like | NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit | NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal |
|---|---|---|---|---|---|---|
|
UniProtKB:Q9MIY0
|
606 |
- Genome Browsers
- No data available
Interactions and Pathways
No data available
Plasmids
No data available