ZFIN is now using GRCz12tu for Genomic Data
Gene
mt-nd5
- ID
- ZDB-GENE-011205-12
- Name
- NADH dehydrogenase 5, mitochondrial
- Symbol
- mt-nd5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: MT Mapping Details/Browsers
- Genome Assembly
- Unknown
- Annotation Status
- Unknown
- Description
- Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in electron transport coupled proton transport; mitochondrial electron transport, NADH to ubiquinone; and mitochondrial respiratory chain complex I assembly. Predicted to act upstream of or within ATP synthesis coupled electron transport. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Is expressed in muscle and skeletal muscle. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and MELAS syndrome. Orthologous to human MT-ND5 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001516 | NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal |
| Domain | IPR001750 | NADH:quinone oxidoreductase/Mrp antiporter, transmembrane domain |
| Domain | IPR010934 | NADH dehydrogenase subunit 5, C-terminal |
| Family | IPR003945 | NADH-quinone oxidoreductase, chain 5-like |
| Family | IPR018393 | NADH-plastoquinone oxidoreductase, chain 5 subgroup |
Domain Details Per Protein
| Protein | Additional Resources | Length | NADH dehydrogenase subunit 5, C-terminal | NADH-plastoquinone oxidoreductase, chain 5 subgroup | NADH-quinone oxidoreductase, chain 5-like | NADH:quinone oxidoreductase/Mrp antiporter, transmembrane domain | NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q9MIY0 | InterPro | 606 |
- Genome Browsers
- No data available
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mt-nd5-201
(1)
|
Ensembl | 1,821 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- No data available