Gene
guca1b
- ID
- ZDB-GENE-011128-6
- Name
- guanylate cyclase activator 1B
- Symbol
- guca1b Nomenclature History
- Previous Names
-
- gcap2
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Enables calcium ion binding activity and calcium sensitive guanylate cyclase activator activity. Predicted to be involved in regulation of guanylate cyclase activity and visual perception. Predicted to be active in cone photoreceptor outer segment and photoreceptor inner segment. Is expressed in retina. Human ortholog(s) of this gene implicated in retinitis pigmentosa 48. Orthologous to human GUCA1B (guanylate cyclase activator 1B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 48 | Alliance | Retinitis pigmentosa 48 | 613827 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair | Recoverin family |
|---|---|---|---|---|---|
|
UniProtKB:Q90WX3
|
197 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
guca1b-201
(1)
|
Ensembl | 1,302 nt |
Interactions and Pathways
No data available
Plasmids
No data available