ZFIN ID: ZDB-GENE-010727-1
Gene Name: ETS variant transcription factor 6
Gene Symbol: etv6    Nomenclature History

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Previous Names: id:ibd2308, ztel (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in embryonic hemopoiesis. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in hematologic cancer (multiple). Is expressed in several structures, including brain; germ ring; intermediate cell mass of mesoderm; mesoderm; and renal system. Orthologous to human ETV6 (ETS variant transcription factor 6).
Genome Resources: Alliance (1),  Gene:114444 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-etv6 N/A 1
MO2-etv6 N/A 1
DISEASE ASSOCIATED WITH etv6 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
acute myeloid leukemia Alliance Leukemia, acute myeloid, somatic 601626
Thrombocytopenia 5 616216
DISEASE ASSOCIATED WITH etv6 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process embryonic hemopoiesis (more)
Cellular Component host cell nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM etv6 No data available
MARKER RELATIONSHIPS
etv6 Encodes: [EST] ibd2308
[cDNA] MGC:55785 (1), MGC:77384 (1), MGC:192902 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131832 (1)
Genomic RefSeq:NW_003337254 (1) Blast at MegaBLAST
Polypeptide UniProtKB:B2GTA2 (1) 444 aa
Sequence Information (all 24)
ORTHOLOGY for etv6 ( Chr: 4 )
CITATIONS (20)