Gene
arf1
- ID
- ZDB-GENE-010724-5
- Name
- ADP-ribosylation factor 1
- Symbol
- arf1 Nomenclature History
- Previous Names
-
- wu:fb33e02
- wu:fb78h01
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity. Acts upstream of or within semicircular canal development. Predicted to be active in cytoplasm and plasma membrane. Is expressed in brain; head; pharyngeal arch 3-7; and semicircular canal. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARF1 (ADP ribosylation factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55900 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Petko et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Periventricular nodular heterotopia 8 | 618185 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR005225 | Small GTP-binding domain |
| Family | IPR006689 | Small GTPase superfamily, ARF/SAR type |
| Family | IPR024156 | Small GTPase superfamily, ARF type |
| Family | IPR045872 | ADP-ribosylation factor 1-5 |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | ADP-ribosylation factor 1-5 | P-loop containing nucleoside triphosphate hydrolase | Small GTPase superfamily, ARF/SAR type | Small GTPase superfamily, ARF type | Small GTP-binding domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q803D1
|
180 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids