Gene

arf1

ID
ZDB-GENE-010724-5
Name
ADP-ribosylation factor 1
Symbol
arf1 Nomenclature History
Previous Names
  • wu:fb33e02
  • wu:fb78h01
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have GTP binding activity. Involved in semicircular canal development. Predicted to localize to cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Is expressed in brain; head; pharyngeal arch 3-7; and semicircular canal. Orthologous to human ARF1 (ADP ribosylation factor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Petko et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arf1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Periventricular nodular heterotopia 8 618185
Associated With arf1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005225 Small GTP-binding protein domain
Family IPR006689 Small GTPase superfamily, ARF/SAR type
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length P-loop containing nucleoside triphosphate hydrolase Small GTPase superfamily, ARF/SAR type Small GTP-binding protein domain
UniProtKB:Q803D1 180
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations