Gene
arf1
- ID
- ZDB-GENE-010724-5
- Name
- ADP-ribosylation factor 1
- Symbol
- arf1 Nomenclature History
- Previous Names
-
- wu:fb33e02
- wu:fb78h01
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity. Acts upstream of or within semicircular canal development. Predicted to be located in Golgi membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in brain; head; pharyngeal arch 3-7; and semicircular canal. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARF1 (ARF GTPase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55900 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Petko et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Periventricular nodular heterotopia 8 | 618185 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR005225 | Small GTP-binding domain |
| Family | IPR006689 | Small GTPase superfamily, ARF/SAR type |
| Family | IPR024156 | Small GTPase superfamily, ARF type |
| Family | IPR045872 | ADP-ribosylation factor 1-5 |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | ADP-ribosylation factor 1-5 | P-loop containing nucleoside triphosphate hydrolase | Small GTPase superfamily, ARF/SAR type | Small GTPase superfamily, ARF type | Small GTP-binding domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q803D1
|
180 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids