Gene
erf
- ID
- ZDB-GENE-010724-17
- Name
- Ets2 repressor factor
- Symbol
- erf Nomenclature History
- Previous Names
-
- fc22h01
- wu:fc22h01
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in craniosynostosis. Is expressed in head. Orthologous to human ERF (ETS2 repressor factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Sun et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| craniosynostosis 4 | Alliance | Craniosynostosis 4 | 600775 |
| Chitayat syndrome | 617180 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ets domain | ETS family | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:B7ZVP1
|
621 | ||||
|
UniProtKB:Q1LY54
|
616 |
Interactions and Pathways
No data available
Plasmids
No data available