Gene
ppp1r12c
- ID
- ZDB-GENE-010724-11
- Name
- protein phosphatase 1, regulatory subunit 12C
- Symbol
- ppp1r12c Nomenclature History
- Previous Names
-
- mypt2
- fi37e03
- wu:fc07c03
- wu:fi37e03
- zgc:152881
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable enzyme inhibitor activity and phosphatase regulator activity. Predicted to act upstream of or within signal transduction. Predicted to be active in cytoplasm. Orthologous to human PPP1R12C (protein phosphatase 1 regulatory subunit 12C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7159189 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR031775 | cGMP-dependent protein kinase, interacting domain |
| Family | IPR017401 | Protein phosphatase 1 regulatory subunit 12A/B/C |
| Family | IPR051226 | Protein Phosphatase 1 Regulatory Subunit |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | cGMP-dependent protein kinase, interacting domain | Protein Phosphatase 1 Regulatory Subunit | Protein phosphatase 1 regulatory subunit 12A/B/C |
|---|---|---|---|---|---|---|
|
UniProtKB:Q08BR9
|
672 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ppp1r12c-201
(1)
|
Ensembl | 3,549 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance
- Gene Tree
- Ensembl
- Note
- Woods, et al (2005. Genome Res. 15:1307-1314) and Rajarao, et al (2001. Genome Res. 11:1211-1220) reported this gene as the ortholog of human PPP1R12B. Subsequent analysis suggests that this gene is the ortholog of human PPP1R12C based on amino acid sequence similarity.