ZFIN is now using GRCz12tu for Genomic Data
Gene
pbrm1l
- ID
- ZDB-GENE-010501-3
- Name
- polybromo 1, like
- Symbol
- pbrm1l Nomenclature History
- Previous Names
-
- pb1 (1)
- zgc:100857
- zgc:113882
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable chromatin binding activity. Predicted to be involved in chromatin remodeling and transcription elongation by RNA polymerase II. Predicted to be part of RSC-type complex and SWI/SNF complex. Human ortholog(s) of this gene implicated in extrahepatic bile duct adenocarcinoma; lung non-small cell carcinoma; lung small cell carcinoma; and renal cell carcinoma. Orthologous to human PBRM1 (polybromo 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu469 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018359 | Bromodomain, conserved site |
| Domain | IPR001025 | Bromo adjacent homology (BAH) domain |
| Domain | IPR001487 | Bromodomain |
| Domain | IPR009071 | High mobility group box domain |
| Domain | IPR037968 | Protein polybromo-1, Bromodomain 5 |
| Family | IPR037382 | Remodelling complex subunit Rsc/polybromo |
| Homologous_superfamily | IPR036427 | Bromodomain-like superfamily |
| Homologous_superfamily | IPR036910 | High mobility group box domain superfamily |
| Homologous_superfamily | IPR043151 | Bromo adjacent homology (BAH) domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Bromo adjacent homology (BAH) domain | Bromo adjacent homology (BAH) domain superfamily | Bromodomain | Bromodomain, conserved site | Bromodomain-like superfamily | High mobility group box domain | High mobility group box domain superfamily | Protein polybromo-1, Bromodomain 5 | Remodelling complex subunit Rsc/polybromo |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7EZ71 | InterPro | 1587 | |||||||||
| UniProtKB:A0A8M2BG23 | InterPro | 1657 | |||||||||
| UniProtKB:A0AB32TT87 | InterPro | 1629 | |||||||||
| UniProtKB:A0AC58JR13 | InterPro | 1603 | |||||||||
| UniProtKB:A0AC58JR21 | InterPro | 1603 | |||||||||
| UniProtKB:A0AC58JR23 | InterPro | 1629 | |||||||||
| UniProtKB:A0AC58JR24 | InterPro | 1657 | |||||||||
| UniProtKB:A0AC58JR26 | InterPro | 1657 | |||||||||
| UniProtKB:A0AC58JR28 | InterPro | 1575 | |||||||||
| UniProtKB:A0AC58JR29 | InterPro | 1575 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pbrm1l-201
(1)
|
Ensembl | 5,481 nt | ||
| mRNA |
pbrm1l-202
(1)
|
Ensembl | 5,449 nt | ||
| mRNA |
pbrm1l-203
(1)
|
Ensembl | 5,611 nt | ||
| mRNA |
pbrm1l-206
(1)
|
Ensembl | 1,475 nt | ||
| ncRNA |
pbrm1l-003
(1)
|
Ensembl | 767 nt | ||
| ncRNA |
pbrm1l-005
(1)
|
Ensembl | 754 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers