Gene
cry3a
- ID
- ZDB-GENE-010426-4
- Name
- cryptochrome circadian regulator 3a
- Symbol
- cry3a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Involved in negative regulation of transcription, DNA-templated; response to light stimulus; and response to temperature stimulus. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome. Is expressed in several structures, including brain; eye; heart; liver; and pleuroperitoneal region. Orthologous to human CRY1 (cryptochrome circadian regulator 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 19 figures from 14 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Delayed sleep phase disorder, susceptibility to} | 614163 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR005101 | Cryptochrome/DNA photolyase, FAD-binding domain |
| Domain | IPR006050 | DNA photolyase, N-terminal |
| Family | IPR002081 | Cryptochrome/DNA photolyase class 1 |
| Homologous_superfamily | IPR014729 | Rossmann-like alpha/beta/alpha sandwich fold |
| Homologous_superfamily | IPR036134 | Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily |
| Homologous_superfamily | IPR036155 | Cryptochrome/photolyase, N-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Cryptochrome/DNA photolyase class 1 | Cryptochrome/DNA photolyase, FAD-binding domain | Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily | Cryptochrome/photolyase, N-terminal domain superfamily | DNA photolyase, N-terminal | Rossmann-like alpha/beta/alpha sandwich fold |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q503J5
|
658 | ||||||
|
UniProtKB:A0A8M1P943
|
659 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cry1ba-201
(1)
|
Ensembl | 2,388 nt | ||
| mRNA |
cry1ba-202
(1)
|
Ensembl | 4,510 nt | ||
| ncRNA |
cry1ba-003
(1)
|
Ensembl | 698 nt |
Interactions and Pathways
No data available
Plasmids
No data available