Gene
glra4a
- ID
- ZDB-GENE-010410-3
- Name
- glycine receptor, alpha 4a
- Symbol
- glra4a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Exhibits extracellularly glycine-gated chloride channel activity. Predicted to contribute to chloride channel activity and glycine binding activity. Involved in several processes, including nervous system development; startle response; and thigmotaxis. Predicted to localize to integral component of plasma membrane; neuron projection; and synapse. Is expressed in eye; hindbrain; myotome; spinal cord; and telencephalon. Orthologous to human GLRA4 (glycine receptor alpha 4 (pseudogene)).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6894068 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- 13 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018000 | Neurotransmitter-gated ion-channel, conserved site |
| Domain | IPR006029 | Neurotransmitter-gated ion-channel transmembrane domain |
| Domain | IPR006202 | Neurotransmitter-gated ion-channel ligand-binding domain |
| Family | IPR006028 | Gamma-aminobutyric acid A receptor/Glycine receptor alpha |
| Family | IPR006201 | Neurotransmitter-gated ion-channel |
| Family | IPR008127 | Glycine receptor alpha |
| Family | IPR008129 | Glycine receptor alpha2 |
| Homologous_superfamily | IPR036719 | Neurotransmitter-gated ion-channel transmembrane domain superfamily |
| Homologous_superfamily | IPR036734 | Neurotransmitter-gated ion-channel ligand-binding domain superfamily |
| Homologous_superfamily | IPR038050 | Neuronal acetylcholine receptor |
Domain Details Per Protein
| Protein | Length | Gamma-aminobutyric acid A receptor/Glycine receptor alpha | Glycine receptor alpha | Glycine receptor alpha2 | Neuronal acetylcholine receptor | Neurotransmitter-gated ion-channel | Neurotransmitter-gated ion-channel, conserved site | Neurotransmitter-gated ion-channel ligand-binding domain | Neurotransmitter-gated ion-channel ligand-binding domain superfamily | Neurotransmitter-gated ion-channel transmembrane domain | Neurotransmitter-gated ion-channel transmembrane domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q9DES9
|
456 | ||||||||||
|
UniProtKB:F1RDZ6
|
457 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
glra4a-201
(1)
|
Ensembl | 2,041 nt | ||
| mRNA |
glra4a-202
(1)
|
Ensembl | 2,262 nt | ||
| ncRNA |
glra4a-002
(1)
|
Ensembl | 855 nt |
Interactions and Pathways
No data available
Plasmids
No data available