Gene
cdk7
- ID
- ZDB-GENE-010320-2
- Name
- cyclin-dependent kinase 7
- Symbol
- cdk7 Nomenclature History
- Previous Names
-
- zgc:85821
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and protein phosphorylation. Predicted to localize to cytoplasm and transcription factor TFIIK complex. Is expressed in several structures, including heart; integument; liver; nervous system; and pleuroperitoneal region. Orthologous to human CDK7 (cyclin dependent kinase 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85821 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Family | IPR037770 | Cyclin-dependent kinase 7 |
| Family | IPR050108 | Cyclin-dependent kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Cyclin-dependent kinase | Cyclin-dependent kinase 7 | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q2V6H0
|
345 | ||||||
|
UniProtKB:Q6NWC5
|
311 |
Interactions and Pathways
No data available
Plasmids
No data available