Gene

rgl2

ID
ZDB-GENE-010131-1
Name
ral guanine nucleotide dissociation stimulator-like 2
Symbol
rgl2 Nomenclature History
Previous Names
  • im:7136742
  • rab2l (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to act upstream of or within small GTPase-mediated signal transduction. Predicted to be active in plasma membrane. Orthologous to human RGL2 (ral guanine nucleotide dissociation stimulator like 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa7429Allele with one point mutationUnknownMissenseENU
sa36250Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With rgl2 Human Ortholog
No data available
Associated With rgl2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019804 Ras guanine-nucleotide exchange factor, conserved site
Domain IPR000159 Ras-associating domain
Domain IPR000651 Ras-like guanine nucleotide exchange factor, N-terminal
Domain IPR001895 Ras guanine-nucleotide exchange factors catalytic domain
Family IPR008937 Ras-like guanine nucleotide exchange factor
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Domain Details Per Protein
Protein Additional Resources Length Ras-associating domain Ras guanine-nucleotide exchange factor, catalytic domain superfamily Ras guanine-nucleotide exchange factor, conserved site Ras guanine nucleotide exchange factor domain superfamily Ras guanine-nucleotide exchange factors catalytic domain Ras-like guanine nucleotide exchange factor Ras-like guanine nucleotide exchange factor, N-terminal Ubiquitin-like domain superfamily
UniProtKB:B3DHC8 InterPro 722
UniProtKB:A0A8M2B5A7 InterPro 744
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 16
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA rgl2-201 (1) Ensembl 2,458 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-119J17ZFIN Curated Data
Contained inBACDKEY-107O6ZFIN Curated Data
EncodesESTIMAGE:7136742Thisse et al., 2004
EncodescDNAMGC:194135ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanRGL26
Amino acid sequence comparison (2)
MouseRgl217
Amino acid sequence comparison (2)
Citations
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