ZFIN is now using GRCz12tu for Genomic Data
Gene
daxx
- ID
- ZDB-GENE-010110-3
- Name
- death-domain associated protein
- Symbol
- daxx Nomenclature History
- Previous Names
-
- si:dz179b20.7
- wu:fd15c03
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription; nucleosome assembly; and regulation of apoptotic process. Predicted to act upstream of or within apoptotic process and chromatin organization. Located in nucleus. Is expressed in several structures, including eye; gill; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in appendiceal neoplasm; islet cell tumor; oral squamous cell carcinoma; ovary epithelial cancer; and pancreatic endocrine carcinoma. Orthologous to human DAXX (death domain associated protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Qi et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Daxx, histone-binding domain | Daxx, histone-binding domain superfamily | Daxx, N-terminal domain superfamily | Daxx, N-terminal Rassf1C-interacting domain |
|---|---|---|---|---|---|---|
| UniProtKB:Q1LUU4 | InterPro | 716 | ||||
| UniProtKB:A0A8M6YWD7 | InterPro | 762 | ||||
| UniProtKB:A0A8M2B6F2 | InterPro | 763 | ||||
| UniProtKB:A0AB32TB48 | InterPro | 715 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers