Gene

daxx

ID
ZDB-GENE-010110-3
Name
death-domain associated protein
Symbol
daxx Nomenclature History
Previous Names
  • si:dz179b20.7
  • wu:fd15c03
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Enables transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription; nucleosome assembly; and regulation of apoptotic process. Predicted to act upstream of or within apoptotic process and chromatin organization. Located in nucleus. Is expressed in several structures, including eye; gill; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in appendiceal neoplasm; islet cell tumor; oral squamous cell carcinoma; ovary epithelial cancer; and pancreatic endocrine carcinoma. Orthologous to human DAXX (death domain associated protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Qi et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With daxx Human Ortholog
No data available
Associated With daxx Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR031333 Daxx, N-terminal Rassf1C-interacting domain
Family IPR005012 Daxx protein
Homologous_superfamily IPR038298 Daxx, N-terminal domain superfamily
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations