ZFIN is now using GRCz12tu for Genomic Data
Gene
tapbp.1
- ID
- ZDB-GENE-010110-2
- Name
- TAP binding protein (tapasin), tandem duplicate 1
- Symbol
- tapbp.1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in antigen processing and presentation of endogenous peptide antigen via MHC class I. Predicted to be located in membrane. Is expressed in primordial germ cell. Human ortholog(s) of this gene implicated in MHC class I deficiency and severe combined immunodeficiency. Orthologous to human TAPBP (TAP binding protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:109814 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?MHC class I deficiency 3 | 620814 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013106 | Immunoglobulin V-set domain |
| Family | IPR008056 | Tapasin |
| Family | IPR050380 | Immune Recognition and Response Modulators |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Immune Recognition and Response Modulators | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin V-set domain | Tapasin |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q1LUU3 | InterPro | 442 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA | tapbp.1-001 (1) | Havana | 1,737 nt | ||
| mRNA |
tapbp.1-201
(1)
|
Ensembl | 1,715 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers