Gene

lbx2

ID
ZDB-GENE-001206-2
Name
ladybird homeobox 2
Symbol
lbx2 Nomenclature History
Previous Names
  • lbx1
  • fc26c12
  • lbx1h (1)
  • wu:fc26c12
  • zgc:92170 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in muscle cell development and regulation of canonical Wnt signaling pathway. Predicted to localize to nucleus. Is expressed in several structures, including fin; hindbrain; mesoderm; musculature system; and presumptive paraxial mesoderm. Orthologous to human LBX2 (ladybird homeobox 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
10 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lbx2 Human Ortholog
No data available
Associated With lbx2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR000047 Helix-turn-helix motif
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Family IPR051892 LBX Family Transcription Factors
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Helix-turn-helix motif Homedomain-like superfamily Homeobox, conserved site Homeodomain LBX Family Transcription Factors
UniProtKB:Q804R0 257
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA lbx2-201 (1) Ensembl 1,815 nt
mRNA lbx2-202 (1) Ensembl 4,545 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations