Gene
lbx2
- ID
- ZDB-GENE-001206-2
- Name
- ladybird homeobox 2
- Symbol
- lbx2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in several processes, including positive regulation of convergent extension involved in gastrulation; positive regulation of non-canonical Wnt signaling pathway; and posterior lateral line development. Acts upstream of or within muscle cell development and regulation of canonical Wnt signaling pathway. Predicted to be located in nucleus. Is expressed in several structures, including fin; hindbrain; mesoderm; musculature system; and presumptive paraxial mesoderm. Orthologous to human LBX2 (ladybird homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 10 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Helix-turn-helix motif | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | LBX Family Transcription Factors |
|---|---|---|---|---|---|---|
|
UniProtKB:Q804R0
|
257 |
Interactions and Pathways
No data available
Plasmids
No data available