Gene

fth1a

ID
ZDB-GENE-000831-2
Name
ferritin, heavy polypeptide 1a
Symbol
fth1a Nomenclature History
Previous Names
  • fth1 (1)
  • fb06g09
  • hm:zeh1145
  • wu:fb06g09
  • wu:fq18c10
  • zeh1145
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have ferric iron binding activity; ferrous iron binding activity; and ferroxidase activity. Predicted to be involved in intracellular sequestering of iron ion. Predicted to localize to cytoplasm. Is expressed in blood; eye; liver; ovary; and testis. Human ortholog(s) of this gene implicated in hemochromatosis type 5. Orthologous to several human genes including FTH1 (ferritin heavy chain 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fth1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hemochromatosis type 5 Alliance ?Hemochromatosis, type 5 615517
Associated With fth1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR014034 Ferritin, conserved site
Domain IPR008331 Ferritin/DPS protein domain
Domain IPR009040 Ferritin-like diiron domain
Family IPR001519 Ferritin
Homologous_superfamily IPR009078 Ferritin-like superfamily
Homologous_superfamily IPR012347 Ferritin-like
Domain Details Per Protein
Protein Length Ferritin Ferritin, conserved site Ferritin/DPS protein domain Ferritin-like Ferritin-like diiron domain Ferritin-like superfamily
UniProtKB:Q9DDT0 177
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations