Gene
wwp2
- ID
- ZDB-GENE-000607-82
- Name
- WW domain containing E3 ubiquitin protein ligase 2
- Symbol
- wwp2 Nomenclature History
- Previous Names
-
- id:ibd1121
- wu:fo87e10
- zgc:154036
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within roof of mouth development. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in brain; germ ring; head; pectoral fin bud; and tail bud. Orthologous to human WWP2 (WW domain containing E3 ubiquitin protein ligase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Nakamura et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000008 | C2 domain |
| Domain | IPR000569 | HECT domain |
| Domain | IPR001202 | WW domain |
| Family | IPR024928 | E3 ubiquitin-protein ligase, SMURF1 type |
| Family | IPR050409 | E3 ubiquitin-protein ligase |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR035983 | HECT, E3 ligase catalytic domain |
| Homologous_superfamily | IPR036020 | WW domain superfamily |
Domain Details Per Protein
| Protein | Length | C2 domain | C2 domain superfamily | E3 ubiquitin-protein ligase | E3 ubiquitin-protein ligase, SMURF1 type | HECT domain | HECT, E3 ligase catalytic domain | WW domain | WW domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PUZ4
|
432 | ||||||||
|
UniProtKB:A0A8M6Z4C8
|
865 | ||||||||
|
UniProtKB:A2VCZ7
|
866 | ||||||||
|
UniProtKB:A0A8M9PYE9
|
824 | ||||||||
|
UniProtKB:F6P346
|
867 |
Interactions and Pathways
No data available
Plasmids
No data available