Gene

pycard

ID
ZDB-GENE-000511-2
Name
PYD and CARD domain containing
Symbol
pycard Nomenclature History
Previous Names
  • apoptosis-associated speck-like protein containing a CARD
  • asc1 (1)
  • ASC (1)
  • zAsc (1)
  • zgc:109874
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Exhibits Pyrin domain binding activity. Involved in defense response to bacterium; innate immune response; and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to localize to cytoplasm. Is expressed in several structures, including digestive system; immune system; integument; periderm; and unfertilized egg. Orthologous to human PYCARD (PYD and CARD domain containing).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
17 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Tyrkalska et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pycard Human Ortholog
No data available
Associated With pycard Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001315 CARD domain
Domain IPR004020 DAPIN domain
Domain IPR033516 CARD8/ASC/NALP1, CARD domain
Homologous_superfamily IPR011029 Death-like domain superfamily
Domain Details Per Protein
Protein Length CARD8/ASC/NALP1, CARD domain CARD domain DAPIN domain Death-like domain superfamily
UniProtKB:Q9I9N6 203
UniProtKB:Q4VBV3 203
UniProtKB:A8E7Q7 203
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations