Gene

arntl2

ID
ZDB-GENE-000509-2
Name
aryl hydrocarbon receptor nuclear translocator-like 2
Symbol
arntl2 Nomenclature History
Previous Names
  • bmal2 (1)
  • bmal2a (1)
  • wu:fj90c09
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Is predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of transcription by RNA polymerase II. Acts upstream of or within circadian rhythm and photoperiodism. Predicted to be located in cytoplasm. Predicted to be part of aryl hydrocarbon receptor complex. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human ARNTL2 (aryl hydrocarbon receptor nuclear translocator like 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arntl2 Human Ortholog
No data available
Associated With arntl2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000014 PAS domain
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Domain IPR013767 PAS fold
Family IPR001067 Nuclear translocator
Homologous_superfamily IPR035965 PAS domain superfamily
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Nuclear translocator PAS domain PAS domain superfamily PAS fold
UniProtKB:Q9IAU1 575
UniProtKB:A0A2R8RSG0 626
UniProtKB:A1A5T9 631
UniProtKB:A0A0R4IH97 631
UniProtKB:Q6NZ12 500
UniProtKB:A0A0R4IR76 486
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations