Gene

bmal2

ID

ZDB-GENE-000509-2

Name

basic helix-loop-helix ARNT like 2

Symbol

bmal2 Nomenclature History

Previous Names

bmal2 (1)
bmal2a (1)
arntl2
wu:fj90c09

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within circadian rhythm and photoperiodism. Predicted to be located in cytoplasm. Predicted to be part of aryl hydrocarbon receptor complex. Predicted to be active in nucleus. Is expressed in telencephalon. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human BMAL2 (basic helix-loop-helix ARNT like 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 7 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With bmal2 Human Ortholog

No data available

Associated With bmal2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000014	PAS domain
Domain	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Domain	IPR013767	PAS fold
Family	IPR001067	Nuclear translocator
Family	IPR050933	Circadian Clock Transcription Factors
Homologous_superfamily	IPR035965	PAS domain superfamily
Homologous_superfamily	IPR036638	Helix-loop-helix DNA-binding domain superfamily