Gene
actn3a
- ID
- ZDB-GENE-000329-9
- Name
- actinin alpha 3a
- Symbol
- actn3a Nomenclature History
- Previous Names
-
- actn3 (1)
- actnl
- zgc:63559
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable actin filament binding activity. Predicted to be involved in actin cytoskeleton organization and muscle cell development. Predicted to be located in actin cytoskeleton. Predicted to be active in several cellular components, including Z disc; cell junction; and cortical actin cytoskeleton. Is expressed in several structures, including musculature system; ovary; pectoral fin; pharyngeal arch 3-7; and segmental plate. Orthologous to human ACTN3 (actinin alpha 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7148639 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Frese et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR001589 | Actinin-type actin-binding domain, conserved site |
Domain | IPR001715 | Calponin homology domain |
Domain | IPR002048 | EF-hand domain |
Domain | IPR014837 | EF-hand, Ca insensitive |
Homologous_superfamily | IPR011992 | EF-hand domain pair |
Homologous_superfamily | IPR036872 | CH domain superfamily |
Repeat | IPR002017 | Spectrin repeat |
Repeat | IPR018159 | Spectrin/alpha-actinin |
Domain Details Per Protein
Protein | Additional Resources | Length | Actinin-type actin-binding domain, conserved site | Calponin homology domain | CH domain superfamily | EF-hand, Ca insensitive | EF-hand domain | EF-hand domain pair | Spectrin/alpha-actinin | Spectrin repeat |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:Q7SYD3 | InterPro | 896 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
actn3a-201
(1)
|
Ensembl | 3,259 nt |
Interactions and Pathways
No data available
Plasmids
No data available