Gene
tnnt3a
- ID
- ZDB-GENE-000322-3
- Name
- troponin T type 3a (skeletal, fast)
- Symbol
- tnnt3a Nomenclature History
- Previous Names
-
- tnnt
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable tropomyosin binding activity; troponin C binding activity; and troponin I binding activity. Acts upstream of or within sarcomere organization. Predicted to be part of troponin complex. Is expressed in musculature system and somite. Human ortholog(s) of this gene implicated in distal arthrogryposis type 2B and distal arthrogryposis type 2B2. Orthologous to human TNNT3 (troponin T3, fast skeletal type).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64197 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Ferrante et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| distal arthrogryposis type 2B2 | Alliance | Arthrogryposis, distal, type 2B2 | 618435 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Troponin | Troponin domain superfamily | Troponin T |
|---|---|---|---|---|
|
UniProtKB:A0A8M2BAI0
|
282 | |||
|
UniProtKB:Q9I8U9
|
230 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tnnt3a-201
(1)
|
Ensembl | 1,138 nt | ||
| ncRNA |
tnnt3a-002
(1)
|
Ensembl | 370 nt |
Interactions and Pathways
No data available
Plasmids
No data available