Gene
urod
- ID
- ZDB-GENE-000208-18
- Name
- uroporphyrinogen decarboxylase
- Symbol
- urod Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Exhibits uroporphyrinogen decarboxylase activity. Involved in porphyrin-containing compound metabolic process. Predicted to localize to cytosol. Used to study hepatoerythropoietic porphyria. Human ortholog(s) of this gene implicated in porphyria cutanea tarda. Is expressed in blood; intermediate cell mass of mesoderm; and presumptive blood. Orthologous to human UROD (uroporphyrinogen decarboxylase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| porphyria cutanea tarda | Alliance | Porphyria cutanea tarda | 176100 |
| porphyria cutanea tarda | Alliance | Porphyria, hepatoerythropoietic | 176100 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| hepatoerythropoietic porphyria | urodtp61/tp61 | standard conditions | (2) |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | UROD/MetE-like superfamily | Uroporphyrinogen decarboxylase HemE | Uroporphyrinogen decarboxylase (URO-D) |
|---|---|---|---|---|
|
UniProtKB:Q9PTS2
|
369 |
Interactions and Pathways
No data available
Plasmids
No data available