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ZFIN ID: ZDB-FISH-150901-4644
Fish name: WT + MO1-spi1b
Genotype: WT
Targeting Reagent: MO1-spi1b
HUMAN DISEASE MODELED by WT + MO1-spi1b
No data available
GENE EXPRESSION
Gene expression in WT + MO1-spi1b
RNA expression
Expressed Gene Structure Conditions Figures
apoeb standard conditions Fig. 4 with image from Peri et al., 2008
cebp1 standard conditions Fig. 3 with image from Kitaguchi et al., 2009
cxcl8a control Figure 2 with image from Hassan-Abdi et al., 2019
cxcr3.2 standard conditions Fig. 3 from Zakrzewska et al., 2010
gata1a standard conditions Fig. 3 from Bukrinsky et al., 2009
Fig. 3 from Sumanas et al., 2008
il1b control Figure 2 with image from Hassan-Abdi et al., 2019
amputation: caudal fin Fig. 5 with image from Hasegawa et al., 2017
lcp1 standard conditions Fig. 1 from Zakrzewska et al., 2010
Fig. 3Fig. 5 from Bukrinsky et al., 2009
Fig. 6 from Clatworthy et al., 2009
lyz standard conditions Fig. 3 with image from Kitaguchi et al., 2009
mfap4.1 standard conditions Fig. 3 from Zakrzewska et al., 2010
mpeg1.1 standard conditions Fig. 3 from Zakrzewska et al., 2010
mpx standard conditions Fig. 3Fig. 5 from Bukrinsky et al., 2009
Fig. 8 with image from Walters et al., 2009
ptpn6 standard conditions Fig. 3 from Zakrzewska et al., 2010
runx1 standard conditions Fig. 3 with image from Kitaguchi et al., 2009
slc7a7 standard conditions Fig. 3 with image from Rossi et al., 2015
spi1a standard conditions Fig. 4 from Bukrinsky et al., 2009
spi1b standard conditions Fig. 4 from Bukrinsky et al., 2009
tnfa standard conditions Fig. 7 from Espín-Palazón et al., 2014
vegfc standard conditions Fig. 8 with image from Helker et al., 2013
Reporter gene expression No data available
PHENOTYPE
Phenotype in WT + MO1-spi1b
Phenotype Conditions Figures
blood island lacks parts or has fewer parts of type granulocyte, abnormal standard conditions Fig. 3Fig. 5 from Bukrinsky et al., 2009
blood island lacks parts or has fewer parts of type macrophage, abnormal standard conditions Fig. 3Fig. 5 from Bukrinsky et al., 2009
blood island macrophage decreased amount, abnormal control Fig. 1 from Tenor et al., 2015
brain lacks all parts of type microglial cell, abnormal standard conditions Fig. 1 with image from Villani et al., 2019
Fig. 3 with image from Rossi et al., 2015
Fig. S7 from Flinn et al., 2013
brain apoptotic cell clearance decreased occurrence, abnormal control Fig. 2 from Mazaheri et al., 2014
brain apoptotic process normal rate, normal standard conditions Fig. 1 with image from Villani et al., 2019
brain phagocytosis decreased occurrence, abnormal standard conditions Fig. 1 with image from Villani et al., 2019
caudal fin regenerating fin il1b expression increased amount, abnormal amputation: caudal fin Fig. 5 with image from Hasegawa et al., 2017
common cardinal vein blood vessel endothelial cell increased amount, abnormal standard conditions Fig. 8 with image from Helker et al., 2013
defense response to fungus process quality, abnormal fungal treatment: Aspergillus fumigatus Fig. 1 from Knox et al., 2014
macrophage decreased amount, abnormal standard conditions Fig. 8 with image from Helker et al., 2013
macrophage decreased amount, abnormal amputation: caudal fin Fig. 4 with image from Hasegawa et al., 2017
microglia development arrested, abnormal standard conditions Fig. S7 from Flinn et al., 2013
microglia development decreased occurrence, abnormal standard conditions Fig. 3 with image from Rossi et al., 2015
microglial cell absent, abnormal standard conditions Fig. 2 from Mazaheri et al., 2014
Fig. 4 with image from Peri et al., 2008
muscle degenerate, abnormal standard conditions Fig. 8 with image from Walters et al., 2009
myeloid cell absent, abnormal standard conditions Fig. 1Fig. 3 from Zakrzewska et al., 2010
neuron axon decreased amount, abnormal standard conditions Fig. 4 from Mikdache et al., 2019
neutrophil decreased amount, abnormal standard conditions Fig. 8 with image from Walters et al., 2009
neutrophil decreased amount, abnormal amputation: caudal fin Fig. 4 with image from Hasegawa et al., 2017
optic tectum microglial cell absent, abnormal control Figure 2 with image from Hassan-Abdi et al., 2019
optic tectum microglial cell ab2-lcp1 labeling absent, abnormal control Figure 2 with image from Hassan-Abdi et al., 2019
posterior lateral line ganglion has fewer parts of type neuron, abnormal standard conditions Fig. 4 from Mikdache et al., 2019
posterior lateral line ganglion has normal numbers of parts of type neuron, normal standard conditions Fig. 4 from Mikdache et al., 2019
posterior lateral line ganglion apoptotic process increased occurrence, abnormal standard conditions Fig. 4 from Mikdache et al., 2019
regenerating fin decreased length, abnormal physical alteration: anatomical structure, chemical treatment: EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor Fig. 2 from Yoo et al., 2012
regenerating fin decreased length, abnormal physical alteration: anatomical structure, chemical treatment: dibenziodolium Fig. 2 from Yoo et al., 2012
regenerating fin apoptotic process increased occurrence, abnormal amputation: caudal fin Fig. 4 with imageFig. 5 with image from Hasegawa et al., 2017
regenerating fin apoptotic process occurrence, ameliorated chemical treatment by environment: dexamethasone, amputation: caudal fin Fig. 5 with image from Hasegawa et al., 2017
regulation of myeloid leukocyte differentiation disrupted, abnormal standard conditions Fig. 3Fig. 4Fig. 5 from Bukrinsky et al., 2009
response to virus process quality, abnormal viral treatment: Chikungunya virus Fig. 7 with image from Palha et al., 2013
whole organism dead, abnormal fungal treatment: Aspergillus fumigatus Fig. 1 from Knox et al., 2014
whole organism il1b expression decreased amount, abnormal control Figure 2 with image from Hassan-Abdi et al., 2019
whole organism cxcl8a expression decreased amount, abnormal control Figure 2 with image from Hassan-Abdi et al., 2019
whole organism tnfa expression decreased amount, abnormal standard conditions Fig. 7 from Espín-Palazón et al., 2014
whole organism decreased life span, abnormal viral treatment: Carp sprivivirus Fig. 6 from Varela et al., 2014
whole organism decreased life span, abnormal viral treatment: Chikungunya virus Fig. 7 with image from Palha et al., 2013
whole organism decreased life span, abnormal fungal treatment: Aspergillus fumigatus Fig. 1 from Knox et al., 2014
whole organism decreased life span, abnormal fungal treatment by injection Fig. 1 from Tenor et al., 2015
yolk lacks parts or has fewer parts of type macrophage, abnormal standard conditions Fig. 3Fig. 5 from Bukrinsky et al., 2009
yolk lacks parts or has fewer parts of type granulocyte, abnormal standard conditions Fig. 3Fig. 5 from Bukrinsky et al., 2009

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