ZFIN ID: ZDB-FISH-150901-29653
Fish name: AB + MO1-atxn7
Genotype: AB
Targeting Reagent: MO1-atxn7
HUMAN DISEASE MODELED by AB + MO1-atxn7
Human Disease Conditions Citations
cone-rod dystrophy standard conditions Carrillo-Rosas et al., 2018
coloboma standard conditions Carrillo-Rosas et al., 2018
nerve fibre bundle defect standard conditions Carrillo-Rosas et al., 2018
GENE EXPRESSION
Gene expression in AB + MO1-atxn7
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in AB + MO1-atxn7
Phenotype Conditions Figures
camera-type eye photoreceptor cell differentiation disrupted, abnormal standard conditions Fig. 8 from Carrillo-Rosas et al., 2018
diencephalon shha expression increased amount, abnormal control Fig. 6 from Carrillo-Rosas et al., 2018
diencephalon pax6a expression mislocalised, abnormal control Fig. 6 from Carrillo-Rosas et al., 2018
embryo development disrupted, abnormal standard conditions Fig. 3 with image from Yanicostas et al., 2012
eye decreased diameter, abnormal standard conditions text only from Carrillo-Rosas et al., 2018
floor plate shhb expression increased amount, abnormal control Fig. 6 from Carrillo-Rosas et al., 2018
forebrain ventral region shhb expression increased amount, abnormal control Fig. 6 from Carrillo-Rosas et al., 2018
histone modification disrupted, abnormal standard conditions text only from Carrillo-Rosas et al., 2018
optic cup unfused from optic cup, abnormal control Fig. 2 from Carrillo-Rosas et al., 2018
optic cup ventral region vax2 expression increased distribution, abnormal control Fig. 6 from Carrillo-Rosas et al., 2018
optic fissure closure incomplete, abnormal control Fig. 2 from Carrillo-Rosas et al., 2018
optic fissure open, abnormal control Fig. 3 from Carrillo-Rosas et al., 2018
optic stalk pax2a expression increased distribution, abnormal control Fig. 6 from Carrillo-Rosas et al., 2018
optic vesicle pax2a expression mislocalised, abnormal control Fig. 6 from Carrillo-Rosas et al., 2018
optic vesicle posterior region pax6a expression mislocalised, abnormal control Fig. 6 from Carrillo-Rosas et al., 2018
photoreceptor cell photoreceptor inner segment malformed, abnormal standard conditions Fig. 8 from Carrillo-Rosas et al., 2018
photoreceptor cell photoreceptor outer segment absent, abnormal standard conditions Fig. 8 from Carrillo-Rosas et al., 2018
photoreceptor cell photoreceptor outer segment decreased length, abnormal standard conditions Fig. 8 from Carrillo-Rosas et al., 2018
posterior segment eye proximal side irregularly shaped, abnormal control Fig. 2 from Carrillo-Rosas et al., 2018
posterior segment eye proximal side lacks parts or has fewer parts of type retinal pigmented epithelium, abnormal control Fig. 2 from Carrillo-Rosas et al., 2018
retina crx expression decreased distribution, abnormal standard conditions Fig. 8 from Carrillo-Rosas et al., 2018
retina crx expression spatial pattern, abnormal standard conditions Fig. 8 from Carrillo-Rosas et al., 2018
retinal neural layer protruding into brain, abnormal control Fig. 3 from Carrillo-Rosas et al., 2018
retinal pigmented epithelium decreased area, abnormal control Fig. 2 from Carrillo-Rosas et al., 2018
retinal pigmented epithelium decreased pigmentation, abnormal standard conditions Fig. 8 from Carrillo-Rosas et al., 2018
somite morphology, abnormal standard conditions text only from Carrillo-Rosas et al., 2018
telencephalon vax2 expression mislocalised, abnormal control Fig. 6 from Carrillo-Rosas et al., 2018
whole organism dead, abnormal standard conditions Fig. 3 with image from Yanicostas et al., 2012
whole organism decreased length, abnormal standard conditions text only from Carrillo-Rosas et al., 2018
whole organism deformed, abnormal standard conditions Fig. 3 with image from Yanicostas et al., 2012

CITATIONS  (3)