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ZFIN ID: ZDB-FISH-150901-23644
Fish name: y1Tg + MO2-cds2
Genotype: y1Tg
Targeting Reagent: MO2-cds2
HUMAN DISEASE MODELED by y1Tg + MO2-cds2
No data available
GENE EXPRESSION
Gene expression in y1Tg + MO2-cds2
RNA expression No data available
Protein expression
Antibody Antigen Genes Structure Conditions Figures
Ab9-mapk control Fig. S8 from Stratman et al., 2020
Reporter gene expression
Expressed Gene Structure Conditions Figures
EGFP standard conditions Fig. 4 from Pan et al., 2012
PHENOTYPE
Phenotype in y1Tg + MO2-cds2
Phenotype Conditions Figures
angiogenesis disrupted, abnormal standard conditions Fig. 2Fig. 3Fig. 4 from Pan et al., 2012
blood vessel endothelial cell decreased amount, abnormal standard conditions Fig. 3 from Pan et al., 2012
central artery decreased amount, abnormal control Fig. S1 from Stratman et al., 2020
hindbrain sprouting angiogenesis decreased occurrence, abnormal control Fig. S1 from Stratman et al., 2020
intersegmental vessel decreased length, abnormal standard conditions Fig. 2Fig. 3Fig. 4 from Pan et al., 2012
intersegmental vessel malformed, abnormal control Fig. 1 with image from Zhao et al., 2019
positive regulation of ERK1 and ERK2 cascade decreased magnitude, abnormal standard conditions Fig. 3Fig. 4 from Pan et al., 2012
positive regulation of vascular endothelial growth factor signaling pathway decreased occurrence, abnormal standard conditions Fig. 3Fig. 4 from Pan et al., 2012
trunk ab9-mapk labeling decreased amount, abnormal control Fig. S8 from Stratman et al., 2020
trunk vasculature malformed, abnormal control Fig. 1 with image from Zhao et al., 2019
whole organism 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate decreased amount, abnormal control Fig. 7 with image from Zhao et al., 2019

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