ZFIN Fish: WT + MO1-tbx5b

ZFIN ID: ZDB-FISH-150901-1970

ZFIN ID: ZDB-FISH-150901-1970

Fish name:	WT + MO1-tbx5b
Genotype:	WT
Targeting Reagent:	MO1-tbx5b

HUMAN DISEASE MODELED by WT + MO1-tbx5b
No data available

GENE EXPRESSION
Gene expression in WT + MO1-tbx5b

RNA expression

Expressed Gene	Structure	Conditions	Figures
bmp4	apical ectodermal ridge pectoral fin bud mesenchyme pectoral fin presumptive atrioventricular canal whole organism	standard conditions	Fig. 5 , Fig. 7 , Fig. 9 from Parrie et al., 2013
efnb2a	retina dorsal region	standard conditions	Fig. 4 from Pi-Roig et al., 2014
ephb2a	retina ventral region	standard conditions	Fig. 4 from Pi-Roig et al., 2014
etv4	mesenchyme pectoral fin pectoral fin ectoderm (not) pectoral fin bud ectoderm	standard conditions	Fig. 5 from Pi-Roig et al., 2014
fgf10a	mesoderm pectoral fin bud	standard conditions	Fig. 5 from Pi-Roig et al., 2014
fgf24	mesenchyme pectoral fin mesoderm pectoral fin bud pectoral fin ectoderm	standard conditions	Fig. 5 from Pi-Roig et al., 2014
hand2	mesenchyme pectoral fin pharyngeal arch presumptive atrium heart tube presumptive cardiac ventricle heart tube	standard conditions	Fig. 5 , Fig. 9 from Parrie et al., 2013
hey2	whole organism	standard conditions	Fig. 7 from Parrie et al., 2013
myl7	heart tube	standard conditions	Fig. 2 from Pi-Roig et al., 2014
nppa	presumptive atrium heart tube presumptive cardiac ventricle heart tube whole organism	standard conditions	Fig. 5 , Fig. 7 from Parrie et al., 2013
tbx2b	whole organism	standard conditions	Fig. 7 from Parrie et al., 2013
tbx5a	mesoderm pectoral fin bud whole organism	standard conditions	Fig. 5 from Pi-Roig et al., 2014 Fig. 7 from Parrie et al., 2013
tbx5b	whole organism	standard conditions	Fig. 7 from Parrie et al., 2013
vcana	(not) apical ectodermal ridge pectoral fin bud otic vesicle presumptive atrioventricular canal presumptive atrium heart tube presumptive cardiac ventricle heart tube	standard conditions	Fig. 5 , Fig. 9 from Parrie et al., 2013

Protein expression No data available

Reporter gene expression No data available

PHENOTYPE
Phenotype in WT + MO1-tbx5b

Phenotype	Conditions	Figures
heart malformed, abnormal	standard conditions	Fig. 1 from Pi-Roig et al., 2014
heart structure, abnormal	standard conditions	Fig. 10 from Parrie et al., 2013
heart development disrupted, abnormal	standard conditions	Fig. 10 from Parrie et al., 2013
heart jogging disrupted, abnormal	standard conditions	Fig. 2 from Pi-Roig et al., 2014
heart looping arrested, abnormal	standard conditions	Fig. 1 from Pi-Roig et al., 2014
heart looping disrupted, abnormal	standard conditions	Fig. 1 from Pi-Roig et al., 2014
pectoral fin decreased size, abnormal	standard conditions	Fig. 8 , Fig. 11 from Parrie et al., 2013
pectoral fin immature, abnormal	standard conditions	Fig. 5 from Pi-Roig et al., 2014
pectoral fin development delayed, abnormal	standard conditions	Fig. 5 from Pi-Roig et al., 2014
pectoral fin development disrupted, abnormal	standard conditions	Fig. 8 , Fig. 11 from Parrie et al., 2013
pectoral fin morphogenesis disrupted, abnormal	standard conditions	Fig. 8 from Parrie et al., 2013

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