FIGURE

Fig. 1

ID

ZDB-FIG-260317-30

Publication

Coomer et al., 2026 - Her9 is required for the migration, differentiation, and survival of neural crest cells

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Fig. 1

Craniofacial phenotypes in her9 mutant zebrafish. A-B) Gross morphology of her9 mutant larvae at 5 dpf compared with WT and heterozygous larvae. Her9 mutants lack a swim bladder (SB, arrow) and have abnormally shaped jaws (arrowheads). C) Absence of swim bladder is a fully penetrant phenotype in her9 mutants. D) Schematic of zebrafish craniofacial structures. E-G′) Variations in her9 mutant craniofacial defects visualized with Alcian blue staining of cartilage. H) Frequency of craniofacial defects observed in her9 vs. WT and heterozygous larvae. I-J) Measurement of distance between the eyes of WT and her9 mutant larvae. Hs, hyosymplectic; bh, basihyal; ch, ceratohyal; m, Meckel's cartilage; pq, palatoquadrate; cb, ceratobranchial arches; hb, hinge bone; tr, trabeculae; ih, interhyal; e, ethmoid plate. Scale bars = 25 μm. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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