FIGURE

Fig. 1

ID
ZDB-FIG-260207-6
Publication
Liu et al., 2025 - Neural-Activity-Regulated Development of Meningeal Lymphatic System in Zebrafish: Novel Mechanism of Brain Self-Cleaning and Neuroimmune Regulation
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Fig. 1

Developmental regulation of meningeal mural lymphatic endothelial cells (muLECs) in zebrafish. slc6a11b+ radial astrocytes (RAs) transport pro-Vegfc to the meninges, where ccbe1+ fibroblasts convert pro-Vegfc into mature Vegfc, thereby restricting muLEC formation to the brain surface. Meningeal lymphatic supporting cells (mLSCs) facilitate muLEC development. muLECs promote the formation of meningeal vessels.

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This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Neurosci. Bull.